24th
Annual International Gravitational
Physiology Meeting

4 - 9 May, 2003
Four Points by Sheraton Santa Monica
California, USA


Hosted by Dr. V. Reggie Edgerton

Sponsored by
the International Society
for Gravitational Physiology

Final Announcement and Call for Papers



Abstract Deadline - 21 March, 2003




IMPORTANT DEADLINES

Abstract Submission
Air Mail Abstract form
to be received by 21 March, 2003
Original to Dr. Peter Norsk with a copy to
Dr. Charles A. Fuller at addresses on the Form.

Registration
Air Mail or fax Registration Form
to be received by 21 March, 2003
to Dr. Reggie Edgerton, with payment
to be received as indicated on the Form.
Note: Registration fees are higher after this date.

Hotel Reservation
Place Hotel Reservations
by 3 April, 2003

Social Events
Our program will include:
*Welcome Reception
*Gala Dinner
*Regional Tour







COUNCIL OF TRUSTEES

OFFICE OF THE CHAIRMAN

P. Norsk, Chairman, Denmark

Peter Norsk, M.D., dr.med.sci.

C.G. Blomqvist, USA

Dept. of Aviation Medicine

A. Cogoli, Switzerland

Section 7522, The Heart Center

V. Convertino, USA

Copenhagen University Hospital

V.R. Edgerton, USA

9 Blegdamsvej

C.A. Fuller, USA

DK-2200 Copenhagen

C. Gharib, France

Denmark

A.I. Grigoriev, Russia

H.G. Hinghofer-Szalkay, Austria

Telephone: +45 35 45 75 76

E. Ilyin, Russia

Telefax: +45 35 45 76 27

K. Kirsch, Germany

E-mail: pnorsk@rh.dk

I.B. Kozlovskaya, Russia

R. Kvetnansky, Slovakia

Future Meetings

T. Mano, Japan

2004 - Russia

J. Seylaz, France

 


16 October, 2002

Dear Colleague:

The International Society for Gravitational Physiology (ISGP) invites the participation of all interested biological scientists to present investigative results in gravitational physiology at the 24th Annual International Gravitational Physiology Meeting to be held in Santa Monica, California May 4-9, 2003. The meeting will be hosted by Dr. V. Reggie Edgerton, Director of the Brain Research Institute and Professor of Physiological Science and Neurobiology, University of California, Los Angeles.

Open sessions will be arranged for slide and poster presentations of voluntary papers dealing with the effects of changes in magnitude and direction of the force environment on the physiology and behavior of humans, animals, plants, and cells. The effects of weightlessness during space flight, acute and chronic acceleration, impact, vibration, and the various forms of simulated weightlessness are included, as well as consideration of the evolutionary consequences of gravity and the role of gravity in the manifestations of scale effects in animals and plants.

Four half-day symposia with invited papers in gravitational physiology will be organized as follows:

Current Concepts in Gravitational Physiology

Effects of Gravity on Plant Physiology

Effects of Gravity on Neurobiological Systems

Biosatellites: Past, Present and Future

It is planned to publish the Proceedings of the meeting, which will contain the voluntary papers and invited symposia papers as a part of the Journal of Gravitational Physiology.

Your participation in the meeting is welcomed. If you wish to participate, either with or without the presentation of a paper, please consult the instructions regarding registration, accommodation, and submission of abstracts, which are provided in the brochure. The deadline for receipt of abstracts is 21 March, 2003.

Peter Norsk, M.D.

Chairman, Council of Trustees


General Information

Organizers
The 24th Annual International Gravitational Physiology Meeting is organized and sponsored by the International Society for Gravitational Physiology (ISGP). Professor V. Reggie Edgerton, President of ISGP, and the Local Organizing Committee are pleased to be the local hosts for the meeting.

Presentation and Publication of Papers
Voluntary papers will be accepted for presentation provided an abstract (in English) is submitted in advance. Oral presentations will be scheduled for the invited symposia and free paper (10 minute) sessions. Slide, LCD and overhead transparency projectors will be available for oral presentations. Poster presentations will be available on boards, measuring approximately 122 cm (4 ft) high and 122 cm (4 ft) wide. At least one Author is expected to be present at the poster during the allotted time. Selection priority for mode of presentation will be given to those participants who pre-register (including registration fee).

Please observe the instructions for preparation of the abstracts. Abstracts must be submitted on the enclosed Abstract Form. The Program and abstracts will be printed for distribution to registrants at the beginning of the Meeting. To appear in the Program, the abstracts must be received at the addresses listed on the Abstract Form on or before 21 March, 2003. Papers presented at the Meeting will be published as the Meeting Proceedings in an issue of the Journal of Gravitational Physiology (papers not presented by an author will not be published). Instructions for the preparation of manuscripts will be provided to all participants who submit abstracts.

Registration and Participation
To facilitate the organization of the meeting, all participants are asked to register by completing the Registration Form and returning it by air mail or fax for receipt on or before 1 March, 2003. Registration fees are $250 (USD) for participants ($300 after 1 March, 2003), $75 for students, and $125 for guests. Advance Payment, payable in US currency, should be sent with the Registration Form to Reggie Edgerton, at the address indicated. The payment may be made by bank check or electronic bank transfer, as indicated on the Registration Form. An 80% refund of registration fees will be made only for cancellations arriving by 1 April, 2003.

Meeting check-in and on-site registration will take place at the Four Points Sheraton Santa Monica Hotel from 15:00 to 18:00, Sunday, 4 May, 2003 and continue daily from 08:00 to 17:00, 5 - 8 May, 2003. Only participants clearly wearing their badges will be admitted to the Meeting Room.

Social Events
Registration includes the following: Welcome Reception on Sunday, 4 May, beginning 19:00 at Four Points by Sheraton Santa Monica; Gala Dinner on Wednesday evening, 7 May; and a regional tour on 9 May. The tour will begin with a drive along the Pacific Coast Highway and a tour of Will Rogers State Park. We will continue through Beverly Hills, stopping at Mann’s Chinese Theatre, Kodak Theatre and the Walk of Fame. The afternoon will be spent at the La Brea Tar Pits and an art museum.

Place of Meeting
Four Points by Sheraton Santa Monica
530 West Pico Boulevard
Santa Monica, CA 90405
Phone: +1-310-399-9344 Fax: +1-310-399-2504
Web Site: http://www.fourpoints.com/santamonica

HOTEL/AIRPORT TRANSPORTATION

From Los Angeles International Airport
Exit onto Sepulveda North. Veer left at fork to Lincoln Boulevard Follow Lincoln for 7 Miles to Pico Boulevard and turn left (west). The hotel is on the left (south) side on Pico between Lincoln and 4th Street.

Airport Shuttle/Taxi Information
LAX Airport Shuttle (www.laxairportshuttle.com) Phone: +1-800-311-5466, $32.00 each way. LAX Shuttle and Limosine (www.laxshuttlelimo.com/services.htm) Phone: +1-877-529-7433, $35.00 each way (towncar).

Supershuttle, email: LAXsales@supershuttle.net, Phone: +1-310-222-5553
Apollo Airport Shuttle, Phone: +1-800-342-9949
Chequer Shuttle, Phone: +1-310-215-9950
Prime Time Shuttle, Phone: +1-800-733-8267

Reservations should be made in advance for shuttle services. Taxi’s are available at a cost of $30-$35 each way. Public transportation is also available on the Big Blue Bus. (www.bigbluebus.com) Take Bus #3 from LAX transit station to Pico and 4th.

Note: Specify Four Points by Sheraton SANTA MONICA, as there is also a Four Points near the Los Angeles Airport.

Local Attractions

Beverly Hills (5 miles) - The infamous home of movie stars and the basis of a very popular TV show. Walk down the streets of Rodeo Drive and Beverly Drive to window shop and see where many movies were filmed. The famous Beverly Wilshire Hotel where Pretty Woman was filmed is found in the heart of Beverly Hills. A great area for sight seeing and possibly spotting a few famous people.

Hollywood Boulevard - The famous “Walk of Fame” where you can search for your favorite celebrity’s star on the sidewalk. Located in the heart of Hollywood is the Mann Chinese Theater as well as the new Kodak Theater where many movie premieres are shown. There is also a brand new shopping center within the Kodak Theater with multi-levels of shopping and brand name stores.

Third Street Promenade (5 blocks) - Located in Santa Monica only a few blocks away from the beach, a series of streets closed off from traffic with shops and restaurants lining the sides. The Promenade spans between Santa Monica Boulevard and Wilshire Boulevard. There are street shows along the Promenade and a shopping mall (Santa Monica Place) at one end. Fun to go for the day if you like the beach environment and great for site-seeing.

Santa Monica Pier (4 blocks) - Located in Santa Monica, right on the beach. Great family attmosphere; play carnival games, and ride the rollercoaster, with the luxury of the beach right at your feet. Food is available there as well.

Downtown Los Angeles - Home to the Staples Center where the Kings and Lakers play during their athletic seasons. Also found there is the fashion district where you can find discount shopping where the importing and exporting of goods take place in the fashion world. The place to go if you like sports and/or are interested in the center of Los Angeles fashion and jewelry world.

Farmer’s Market - Located in East Los Angeles in the Fairfax district. Restaurants, Shops, and site-seeing all within a confined area. Excellent place to go for breakfast and to purchase souvenirs. Across the street from CBS entertainment.

Getty Museum (8 miles) - Located off of Sepulveda Boulevard in West Los Angeles. It overlooks all of West Los Angeles and on a clear day you can see all the way to downtown. It has a beautiful garden to walk through as well as three stories of beautiful artwork displayed. There are also shops and restaurants.

LACMA and Miracle Mile - The Los Angeles County Museum of Art (LACMA) is located on the Miracle Mile along with the Car Museum and other Los Angeles museums and famous buildings. The La Brea Tar Pits are also nearby, which can be walked through. Restaurants are located throughout the area. A good place to go if you are interested in art and the history of Los Angeles.

Burbank - Found in the San Fernando Valley, Burbank is the home of the TV and music industry. Many television studios, such as Disney and ABC are located here. Although there are not many places to walk around, it is a good place to drive through to see the different studio lots.

Universal City - Home to Universal Studios and Universal City Walk. Great place to spend a day. Begin at the studio taking the tour and enjoying amusement park rides within the studio park. Afterwards, you can enjoy shopping and dinner along the City Walk strip. Great place for families.

Disneyland - Located in Anaheim about 45 minutes south of Westwood. Home of Mickey Mouse, this amusement park has rides for older children and adults as well as various themed lands for the littler ones. The famous Disneyland is comparable to Disney World in Florida, and takes at least an entire day to fully enjoy.

Six Flags Magic Mountain - Located in Valencia about 45 minutes north of Westwood. More appropriate for adults than for children, this amusement park offers more rides that are faster and scarier. Great fun for the family that likes roller coasters. The children’s section of the park based on Looney Tunes and Bugs Bunny theme. There are also games and restaurants within the park. Like Disneyland, an all day event.




Instructions for Typing Abstracts

Since the abstract will be photographed from the author’s typescript, it will be published exactly as typed in the outline box. Please read these instructions carefully before typing your abstract.

• Your entire abstract must fit within the outlined box (11.4cm x 16.5cm or 4.5” x 6.5”). We suggest that you practice typing the abstract in a similar rectangle on plain paper before using the special form.

• Do not make carbon copies while typing the abstract on the special form.

• Use black printouts from an ink or laser printer or use an electrical typewriter with a black ribbon. Any insertions must be written in black ink.

• Do not erase. All smudges will show in the published abstract.

• Make abstracts as informative as possible. State specific objectives of study, methods used, a summary of results obtained, and conclusions reached.

Note Especially:

• The title is in capital letters.

• Author(s) name(s) in capital letters and underlined.

• Institution, city, and country where the research was performed.

• Use standard abbreviations only.

• Three (3)-space indention for the first line of abstract.

• Please use 10 pitch Times New Roman character, or similar.

• Abstracts should be one (1) paragraph, typed single spaced.

• No margin at top or left side.

• Fold the form only as indicated. Use cardboard when mailing.

• Provide full address, including email address(es).

Receipt of abstracts will be acknowledged via email. The Program, indicating time and mode of presentation, will be available at the ISGP web site (http://www.isgp.org) by 31 March, 2003.


Please pay Registration Fee by 1 March, 2003 either by:

Certified Bank Check or personal check drawn from a US bank payable in US dollars to:

“International Society for Gravitational Physiology”

Mail registration fee, including Registration Form to:

V. Reggie Edgerton
Departments of Physiological Science and Neurobiology
University of California
621 Charles E. Young Drive South
Los Angeles, CA 90095-1527

OR

Electronic Bank Transfer payable in US dollars

The following information must being included with electronic bank transfer:

Name of registrant

International Society for Gravitational Physiology
621 E. Young Drive South
Los Angeles, CA 90095

Bank Routing Number: 122000496
Account Number: 0360030091
Bank Address:
Union Bank of California
Westwood #6
1310 Westwood Blvd.
Los Angeles, CA 90024
Phone: +1-800-238-4486


MEETING SITE HOTEL ACCOMMODATIONS

A limited number of rooms have been held at a special price of $110 until April 4, 2003 at the Four Points by Sheraton Santa Monica, where the meeting will be held.

Four Points by Sheraton Santa Monica
530 W. Pico Blvd. Santa Monica, CA
Phone: +1-310-399-9344 Fax: +1-310-399-2504
http://www.fourpoints.com/santamonica

The rates given are quoted per room, per night and do not include Room Tax (12.045%). Free self-parking is available.

ALTERNATE HOTEL ACCOMMODATIONS

Alternate accommodations are also available at the following hotels:

Comfort Inn
2815 Santa Monica Boulevard
Santa Monica, CA 90404
Phone: +1-310-828-5517
Web site: http://www.comfortinn.com/
online reservation for 1 person = $65.00
online reservation for 2 people = $75.00

Days Inn
3007 Santa Monica Boulevard
Santa Monica, CA 90404
Phone: +1-310-829-6333
$99.00 per room/night

Best Western Gateway
1920 Santa Monica Boulevard
Santa Monica, CA 90404
Phone: +1-310-829-9100
Standard rate between $94.00-99.00

The alternate hotel room rates are quoted per room, per night, and are subject to change without notice. Participants are advised to make reservations early, as rates will increase for the tourist season.

RESERVATION AND PAYMENT
Note: the Hotel Reservation Form on the following page should be used for Four Points by Sheraton reservations only. All other hotel reservations should be made via contacting the hotel of their choice directly. Reservations must be guaranteed with a credit card at the time of reservation. All major credit cards are accepted (Visa, Mastercard, American Express, Diners Club). To guarantee Sheraton’s reduced room rate, please inform the reservation staff you will be attending the 24th International Gravitational Physiology Meeting.

CANCELLATION
In the event a hotel reservation must be cancelled, notice must be received by 72 hours prior to 6:00pm on the arrival date. In the case of non-arrival, the first night’s deposit will be charged to your credit card.



24th International Gravitational Physiology Meeting

4-9 May, 2003, Santa Monica, California

FINAL PROGRAM


SUNDAY, MAY 4TH

15:00 – 17:00 Meeting check-in and Registration

19:00 Welcome Reception


MONDAY, MAY 5TH

CURRENT CONCEPTS IN GRAVITATIONAL PHYSIOLOGY

08:00 Overview of Study Design and Effects of long-Duration Bedrest with or without Resistance Exercise on Skeletal Muscle Size and Function

P.A. Tesch

08:30 Skeletal Muscle Protein Composition with 84 d of Bedrest and Exercise

T. Trappe

09:00 Effects of Long-Duration Bedrest and Resistance Exercise on Myonuclei and Satellite Cells

L.E. Thornell

09:30 MORNING BREAK

10:00 Human Single Muscle Fiber Function with 84-d Bedrest and Resistance Exercise

S. Trappe

10:30 Effects of Long-Term Bed Rest on Muscle Integrity and Cytoskeletal Proteins with and without Resistance Exercise

A. Chopard

11:00 Skeletal Muscle Marker Expression Following 84d of Bedrest with and without Exercise: Maintenance of NOS-1 Enzyme Activity and Protein

D. Blottner and B. Schoser

11:30 LUNCH

FREE PAPERS: MUSCULOSKELETAL

13:00 Irreversible Morphological Changes in Hindlimb Bones of Rats Following Chronic Unloading

Y. Ohira and F. Kawano

13:15 Effects of Long-Term Bed Rest on Muscle Integrity and Cytoskeletal Proteins With and Without Resistance Exercise

A. Chopard, N. Arrighi, A. Carnino, and J.-F. Marini


13:30 Role of the Gravity Factor on Mechanical Properties and Expression of Contractile Proteins in Rat Soleus Muscles

Y. Mounier, C. Bozzo, F. Picquet, L. Stevens, V. Montel, B. Bastide, and M. Falempin

13:45 Changes of Bone Characteristics under Simulation of Space Flight Condition as Deduced by EPR Spectroscopy

A.B. Brik, O.N. Atamanenko, and V.B. Atamanenko

14:00 High Calcium Intake does not Prevent Disuse-Induced Bone Loss

M. Heer, A. Boese, N. Baecker, and S.M. Smith

14:15 Effects of Artificial Support Stimulation on Soleus Single Fiber Characteristics in Men Exposed to 7-day “Dry” Immersion

K.S. Litvinova, T.L. Nemirovskaya, N.M. Gasnikova, I.B. Kozlovskaya, and B.S. Shenkman

14:30 Effects of Ca2+ Binding Agent on Contractile Characteristics of Single Skinned Soleus Fibers in Hindlimb Suspended Rats

K.S. Litvinova, T.L. Nemirovskaya, and B.S. Shenkman


14:45 AFTERNOON BREAK

FREE PAPERS: COUNTERMEASURES/APPLIED

15:00 Space Shuttle versus Space Station Missions: Cardiovascular Considerations

C.F. Sawin

15:15 Effects of Simultaneous Load of Centrifuge-Induced Artificial Gravity and Ergometer Exercise as the Countermeasures for Space Deconditioning on Human Cardiovascular Function

S. Iwase, Q. Fu, A. Kamiya, D. Michikami, T. Mano, E. Morimoto, and H. Takada

15:30 Development of a Vibration Based Countermeasure to Inhibit the Bone Erosion and Muscle Deterioration that Parallels Spaceflight

T. Kaplan, Y.-X. Qin, S. Judex, and C. Rubin

15:45 Is Intermittent Artificial Gravity an Ideal Multi-System Countermeasure?

L.-F. Zhang, and B. Sun

16:00 The Veno-Arteriolar Response is Preserved Following Long-Term Exposure to Microgravity

A. Gabrielsen and P. Norsk

FREE PAPERS: DEVELOPMENT

16:15 Positive Geotaxis in Infant Rat: Correcting an Historically Misinterpreted Phenomenon

J.R. Alberts and B. Motz

16:30 Effects of Hypergravity Rearing on Growth Hormone and Insulin-Like Growth Factor in Rats

L.A. Baer, J.H. Chowdhury, R.E. Grindeland, C.E. Wade, and A.E. Ronca

16:45 Gender Differences in the Effect of Hypergravity on the Rat Neonatal CNS

K. Nguon and E.M. Sajdel-Sulkowska


17:00 – 18:00 POSTER SESSION I

1 Correlated Resting CA2+ and CA2+ Entry Decreases Precede Slow-to-Fast Transition in Unloaded Rat Soleus Muscle Independently of Atrophy

F. Bodvael, J.-F. Desaphy, S. Pierno, A. De Luca, A. Liantonio, J.-F. Rolland, and D. Conte Camerino

2 Charateristics of Spindle Discharges of Rat Soleus Muscle after a Period of Hypodynamia-Hypokinesia

M. Falempin, L. De-Doncker, and F. Picquet

3 Expression of Myosin Heavy Chain Isoforms in Spindle From Rat Soleus Muscle in Conditions of Microgravity and Hypergravity

M. Falempin, L. De-Doncker, and F. Picquet

4 The Effects of 90-Day 2G Exposure on Muscle Myosis Heavy Chain Expression in Rat Soleus and Plantaris Muscles

J.C. Fuller, P.M. Fuller, C.E. Wade, L.A. Baer, and C.A. Fuller

5 Effects of Hindlimb Unloading on Cell Body Size and Oxidative Enzyme Activity of Soleus Motoneurons in Developing Rats

A. Ishihara, F. Kawano, X.-D. Wang, and Y. Ohira

6 Dynamics of Muscle Transverse Stiffness under Conditions of Dry Immersion in Combination with Artificial Stimulation of Foot Support Zones

D.V. Popov, O.L. Vinogradova, and I.B. Kozlovskaya

7 Myosin Phenotype and Sarcomeric Cytoskeletal Proteins in Stretched Soleus of Hindlimb Suspended Rats

B.S. Shenkman, T.L. Nemirovskaya, I.M. Vikhlyantsev, A.M. Muchina, and Z.A. Podlubnaya

8 Ultrastructural Adaptations of Peripheral Part of Rat Motor Units after Support Unloading, Hypergravity, Combination of the Both Factors, Endurance Exercises (RUN) and Later on Triton Space Flight

M.M. Umnova, I.B. Krasnov, T.P. Seene, and V.I. Mitashov

9 Load-Associated Growth of Soleus Muscle Fibers in Rats

X.D. Wang, F. Kawano, Y. Takeno, H.J. Song, A. Ishihara, and Y. Ohira

10 Effect of Inhibited L-Ca-2+ Channels on Intermittent Tetanic Contraction in Unloading Soleus

F. Gao, Z.-B. Yu, J.-H. Cheng, and J.-P. Jin

11 Changes in Muscle Function after 28-Day Limb Suspension

T. Finni, A.M. Lai, J.A. Hodgson, V.R. Edgerton, and S. Sinha

12 Load- and Afferent-Input-Associated Responses of Neuromuscular System to Hindlimb Unloading in Rats

F. Kawano, A. Ishihara, J.L. Stevens, X.D. Wang, S. Ohshima, M. Horisaka, Y. Maeda, I. Nonaka, and Y. Ohira

13 The Dosed Hypoxia Preserve the Bones Biomechanikal Properties

V.A. Berezovskiy, H.G. Chaka, and P.V. Laxin

14 Effects of Intermittent Standing on Femur of Hindlimb Unloaded Rats

X.-S. Cao, X.-Y. Wu, Y.-H. Wu, and L.-F. Zhang

15 The Bone Electrical Properties in Hypokinetic Rats

M.I. Levashov, V.A. Berezovskiy, S. Saphonnov, and O. Levashov


16 Acclimatization to Hypergravity

J. Sykora, I. Lokcova, J. Dvorka, M.-B. Bachrack, and D. Strobl

17 Re-Adaptation to 1-G of Pregnant Rats Following Exposure to Spaceflight or Centrifugation

K.E. Johnson, J.R. Alberts, and A.E. Ronca


TUESDAY, MAY 6TH

EFFECTS OF GRAVITY ON PLANT PHYSIOLOGY

08:00 Gravisensing in Plants - Many Adaptive Possibilities

K.H. Hasenstein

08:30 Transcription Profileing the Early Gravitropic Response in Arabidopsis Using High-Density Oligonucleotide Probe Microarrarys

N. Moseyko and L. Feldman

09:00 Effects of Extracellular ATP on Growth and Graviresponsiveness in Arabidopsis Roots

W. Tang, I. Steinebrunner, Y. Su, and S.J. Roux

09:30 MORNING BREAK

10:00 Physiological Challenges to Seed Production during Spaceflight

M. Musgrave

10:30 Mapping the Way to Plant Gravitropic Response Genes

T. Lomax

11:00 Spirals in Space - Non-Random Orientation of Moss Protonemata in Microgravity (STS-87)

V. Kern

11:30 LUNCH

FREE PAPERS: PLANT PHYSIOLOGY

13:00 Rearrangements of the In Brassica Rapa Photosynthetic Apparatus in Microgravity

N.I. Adamchuk, E.L. Kordyum, and J.A. Guykema

13:15 Gravity Effects on the Arabidopsis Transcriptome

R. Hampp, M. Martzivanou, R.-M. Maier, E. Magel

13:30 Gravisensing - the Combined Result of Viscous Properties and Noise Amplification

K.H. Hasenstein, Z. Ma, and P. Scherp

13:45 Response of Haplopappus Cells in Callus Culture to Fast Clinorotation

D.O. Klymchuk

14:00 A Role of Cytoskeleton in Plant Cell Gravisensitivity

E.L. Kordyum

14:15 Investigation of the Rheology of the Chara Cytoplasm by Intracellular Magnetograviphoresis of Statoliths

O.A. Kuznetsov

14:30 Vibration Forces and Ultrastround Can Displace Organelles Inside Plant Gravireceptor Cells

O.A. Kuznetsov

14:45 Geotaxis in Pea and Bean Seedlings

G.C. Vezzoli and A. Tse


15:00 Bioconvection in Cultures of the Calcifying Unicellular Alga Pleurochrysis carterae

D. Montufar-Solis, P.J. Duke, and M. Marsh


15:15 AFTERNOON BREAK


FREE PAPERS: CELLULAR/MOLECULAR

15:30 Microgravity and Bone Cell Mechanosensitivity - Fluid Shear Stress-Induced Nitric Oxide Production by Bone Cells is Rate Dependent

R.G. Bacabac, T.H. Smit, S. Dijcks, J.J.W.A. van Loon, and J. Klein-Nulend

15:45 Loss of Pleiotropic Response in Microgravity Accompanied by Changes in Nuclear Morphology

M. Hughes-Fulford, K. Rodenacker, and U. Jutting

16:00 Demonstrate on Line Cell Shape Changes due to Gravity

J.J.W.A. van Loon, M.C. van Laar, J.P. Korterik, F.B. Segerink, R.J. Wubbels, H.A.A. de Jong, and N.F. Van Hulst

16:15 Influence of Artificial Gravity Loading on Synaptosomal Uptake and Release of L-[14C]-Glutamate

T. Borisova, N. Krisanova, N. Himmelreich

FREE PAPERS: ENDOCRINOLOGY/IMMUNOLOGY

16:30 Changes of Urine Volume with Day and Responses of Hormones during 20 Days of Head Down Bed Rest

Y. Suzuki, H. Kobayashi, and A. Gunji

16:45 The Hematopoietic Stem Cell Therapy for Exploration of Deep Space

S. Ohi, A.-N. Roach, W. Fitzgerald, D.A. Riley, and S.R. Gonda

17:00 Energy Intake and Expenditure of Rats Hind Limb Suspended for 90-Days

C.E. Wade, L.A. Baer, P.M. Fuller, T.P. Stein, and C.A. Fuller

17:15 – 18:00 POSTER SESSION II

1 The Effects of Clinorotation on G1-Phase Events in Pea Root Meristematic Cells

O.A. Artemenko

2 Clinostation Influence on Microspectral Parameters of Fluorescence in Healthy and Virus Infected Apogee Wheat Variety Leaves

L.T. Mishchenko, O.I. Kitaev, I.A. Mishchenko, and G.S. Yanishevska

3 Dynamic of the WSMV Reproduction in the Apogee Wheat Variety under Simulated Microgravity Conditions

L.T. Mishchenko

4 Gravitropism of the Statolith-Free Internodal Cells of Chara

M.P. Staves and A. Faber

5 An Effect of Silicon on Biochemical Processes in Plants in Microgravity

N. Zaimenko and T. Cherevchenko

6 Gravicurvature Loss, Changes in Ultrastructure and Calcium Balance of Pea Root Statocytes Treated with Chlorpromazine

N.A. Belyavskaya


7 Ruthenium Red-Induced Gravicurvature Loss, Changes in Statocyte Ultrastructure and Calcium Balance of Pea Seedlings

N.A. Belyavskaya

8 Accumulation of the Nutrient Substances in the Brassica Rapa Embryos and Ovules at Early Stage of their Development under Altered Gravity

A.F. Popova and A.G. Kononko

9 Ultrastructural Subnucleolar Localization of Fibrillarin, One of the Most Important Proteins of Pre-rRNA Processing, is Changed in Altered Gravity

M.A. Sobol

10 Effects of Rotating Clinostat Simulated Weightlessness on the MAPK/ERK Signal Pathway in Osteoblastic ROS 17/2.8 Cells Induced by BMP-2

B. Wang, S. Zhang, and X.-Y. Wu

11 Gene Expression of Paxillin and Talin in Osteoblasts during Weightlessness Simulation using Clinostat

S. Zhang, B. Wang, Y.-H. Wu, and Y.-H. Li

12 Simulated Microgravity Inhibits Proprioceptive-Mediated Secretion of Bioassayable Growth Hormone

R.E. Grindeland, A.J. Bigbee, K.L. Gosselink, R.R. Roy, H. Zhong, L. Baer, T. Wang, M. Moran, and V.R. Edgerton

13 The Effects of Diet and/or Exposure to Acute Stress by Hindlimb Suspension on Estrous Cycling in Female Rats

J.C. Tou, R.E. Grindeland, and C.E. Wade

14 Expression of Components of Vascular Renin-Angiotensin System in Simulated Weightless Rats

J.-X. Bao, Q.-J. Meng, L.-F. Zhang, and L.-N. Zhang

15 Hypergravity-Induced Changes in Hematological and Lymphocyte Function Parameters in a Mouse Model

D.S. Gridley, G.M. Miller, G.A. Nelson, and M.J. Pecaut



WEDNESDAY, MAY 7TH

BIOSATELLITES: PAST, PRESENT AND FUTURE

08:00 Animals and Biosatellites in Space: A Historical Perspective

C.M. Tipton

08:30 The Bion Program and Medical Support of Humans in Space

E.A. Ilyin

09:00 The Main Results of Sensory-Motor Studies in Bion Flights and Their Applications for Human Space Flights

I.B. Kozlovskaya

09:30 MORNING BREAK

10:00 Effects of Head-Out Water Immersion on Eye-Head Coordination in Rhesus Monkeys

A.M. Badakva, N.V. Miller, and J.N. Eron

10:30 Molecular, Cellular and Integrated Muscle Physiology in Microgravity: Past, Present and Future - Neurophysiological Approaches

M. Falempin

11:00 Molecular, Cellular and Integrated Muscle Physiology in Microgravity: Past, Present and Future - Biomolecular Approach and Post-Translational Modifications

Y. Mounier

11:30 LUNCH

FREE PAPERS: BIOSATELLITE / TECHNICAL

13:00 The Mars Gravity Biosatellite: a New Platform for Partial Gravity Research

E.L. Brown, C.E. Carr, and P.D. Wooster

13:15 European SOYUZ Missions - Limitations to Biology Experimentation

J. Maroothynaden

13:30 Hicop: Human Interface Computer Program

F. Beckers, B. Verheyden, and A.E. Aubert

13:45 A Description of Very Large, Commercial R&D Facilities to be Built in Orbit during this Decade

G. Meyers

14:00 Intrauterine Pressure (IUP) Telemetry in Pregnant and Parturient Rats: Potential Applications for Spaceflight and Centrifugation Studies

A.E. Ronca, J.C. Villarreal, L.A. Baer, and C.E. Wade

14:15 Pulsed Phase Lock Loop Device for Monitoring Intracranial Pressure during Space Fight

T. Ueno, B. Macias, W.T. Yost, and A.R. Hargens

14:30 In Vivo Near-Infrared Spectroscopy in Human Bone and Skeletal Muscle

M. Klasing and J. Zange

14:45 Microgravity Effects in Belousov-Zhabotinskii (BZ) Reaction

J.R. Castilho Piqueira


15:00 AFTERNOON BREAK


15:15-17:15 BIOSATELLITE ROUND TABLE DISCUSSION

Round Table panel members:

Dr. Eugene A. Ilyin, Institute of Biomedical Problems, Moscow, Russia

Dr. Noriaki Ishioka, NASDA Headquarters, Tokyo, Japan

Dr. Terri Lomax, NASA Headquarters, Washington, D.C.

Dr. Ketheth Souza, NASA Ames Research Center, Moffett Field, CA

Dr. Charles M. Tipton, University of Arizona, Tucson, AZ

Dr. Michel Viso, ESA Headquarters, Paris, France


15:15 Biosatellites: Recapturing Missed Opportunities and Recommendations for the Future

C.M. Tipton

15:25 Free Flyers: A Research Platform to Augment the International Space Station

K.A. Souza and M. Skidmore

15:35 Bion/Foton Capabilities and Tentative Research Program

E.A. Ilyin

15:45 ROUND TABLE DISCUSSION – OPEN TO ALL PARTICIPANTS

18:00 BUSES DEPART FOUR POINTS SHERATON FOR GALA DINNER

19:00 GALA DINNER


THURSDAY, MAY 8TH

EFFECTS OF GRAVITY ON NEUROBIOLOGICAL SYSTEMS

08:00 Mechanisms of Postural Control in Quadrupeds

T. Deliagina

08:40 Changes in Neural Control of Movement Following Chronic Exposure to Reduced Gravity

V.R. Edgerton

09:20 MORNING BREAK

09:50 Support / Weight-Bearing Afferentation Withdrawal in the Motor System

I.B. Kozlovskaya

10:30 Multi-Parallel CNS Control Mechanisms in Bipedal Walking Japanese Monkeys, M. fuscatat

F. Mori

11:10 LUNCH

13:00 Motor Adaptation to Robotic Force Fields Applied during Locomotion

D. Reinkensmeyer

FREE PAPERS: NEUROBIOLOGICAL SYSTEMS

13:40 Effects of +Gz on Memory and Brain Heat Shock Protein 70 Expression in Rats

X.-Q. Sun, X.-S. Cao, and J.-S. Li

13:55 Mechanical Stimulation of Receptor Cells in Otoliths

A.V. Kondrachuk

14:10 The Model of the Effect of Strong Magnetic Fields on Orientation and Growth of Biological Structures

A.V. Kondrachuk

14:25 The Actions of Helio- and Geomagnetic Disturbance on Human Health and Professional Functioning Reliability on Development of Social Processes

A.I. Mikhailov, G.V. Shilov, P.M. Shalimov, Y.I. Gurfinkel, and V.L. Voeikov

14:40 AFTERNOON BREAK

FREE PAPERS: CARDIOVASCULAR

14:55 Calf Vein Cross Section Changes during Post 7d HDT Stand Test & LBNP in Tolerant & Non-Tolerant Subjects

P. Arbeille, L. Pascaud, F. Belin de Chantemele, M. Porcher, and J. Boulay

15:10 Flow Redistribution Between Legs and Brain during STS 93 Re-entry and Landing. (Case Report)

P. Arbeille, J. Meck, M. Porcher, E. Benavides, D.S. Martin, D.A. South, C. Ribeiro, and A. Westover


15:25 Portal Vein Flow Volume and Diameter Changes during Stand Test in Normal Subjects

P. Arbeille, J. Ayoub, S. Besnard, and L. Pascaud

15:40 Simulated Weightlessness Decreases Potassium Channel Function of Vascular Smooth Muscle Cells of Cerebral Arteries in Rats

Z.-J. Fu, H.-W. Cheng, L.-F. Zhang, and J. Ma

15:55 Effects of Hindlimb Unweighting on Arterial Contractile Responses in Mice

J. Ma, X.-L. Ren, and R.E. Purdy

16:10 Heart Rate Variability during Head Out of Water Immersion: a Simulation of Microgravity?

B. Verheyden, F. Beckers, and A.E. Aubert

16:25 Evolution of Heart Rate Variability before, during and after Space Flight

F. Beckers, B. Verheyden, and A.E. Aubert

16:40 Frequency Analysis of Cardiovascular Variability during Parabolic Flight

B. Verheyden, F. Beckers, and A.E. Aubert

16:55 Cardiovascular Reflexes in Anesthetized Post-Suspension Rat

V.O. Golubinskaya, O.S. Tarasova, A.S. Borovik, and O.L. Vinogradova

17:10 – 18:00 POSTER SESSION III

1 Microgravity Exposure May Modify the Control of Limb Endpoint Movement during Human Walking

G. Courtine, C. Papaxanthis, and T. Pozzo

2 Intermittent 2G Prevents the Structural Alterations in Nervous System of Tail-Suspended Rats

L.N. Dyachkova, I.B. Krasnov, T.D. Burtseva, I.V. Denisenkova, V.S. Yakushina, G.M. Piskunova, V.I. Loginov, and N.A. Chelnaya

3 The Role of the Hystaminergic Neurostransmitter System on Physiological Responses to Hypergravity

P.M. Fuller and C.A. Fuller

4 Changes of Coherences of the Electroencephalogram during an Acceleration of +2.5Gz and Related Performace of Pilot Candidates with Acceleration Training on a Human Centrifuge

D. Wirth, H. Welsch, M. Nehring, F. Noack, P. Lindner, P. Dettmar, and U. Buhss

5 Na+ Dependent Glutamate Efflux from Rat Brain Synaptosomes under Altered Gravitational Environment

T. Borisova, N. Krisanova, N. Himmelreich

6 Reaction of Rat Right Atrium Cardiomyocytes to Simulated Weightlessness

L.S. Pogodina, M.V. Shornikova, and Yu.S. Chentsov

7 Comparison of Heart Rate Response to + and -Gz Load Changes at Safe and Low Altitude Level during Real Flight

P. Dosel, J. Hanousek, J. Petricek, J. Cmiral, and L. Cettl

8 Structural Changes of Brain Vesssels in the Rats Exposed to Prolonged Hypergravity

T.S. Gulevskaya, V.A. Morgunov, and I.B. Krasnov

9 Gravity and Cardiovascular Regulation: Combined Stimulation Paradigm

H. Hinghofer-Szalkay, I. Loder, K. Pilz, and A. Rössler


10 Responses of Rat Left Ventricle Cardiomyocytes to Simulated Weightlessness

T.V. Lipina, M.V. Shornikova, and Yu.S. Chentsov

11 Role of Baroreflex Control of Sinus Node in Orthostatic Intolerance after 4 Hours Head Down Bed Rest

G. Raimondi, J.M. Legramante, S. Sacco, S. Contini, M. Pallante, A. Vespa, and C. Saltini

12 Cardiovascular Responses to Head-Up Tilt Together with Lower Body Negative Pressure Following Exposure to Head-Down Tilt (Simulated Push-Pull Effect)

Y.-J. Yao, X.-Q. Sun, C.-B. Yang, T.-S. Liu

13 Hypoxic Gaz Mixture Partially Compensate Negative Influences of Hypokinesia

I.G. Litkova and V.A. Berezovskiy

14 Cerebral Lateralization and Intelligence in Simulated Microgravity: A Functional Transcranial Doppler Study

P.C. Njemanze


FRIDAY, MAY 7TH

08:45 Board buses at Four Points Sheraton for regional tour

09:00 – 18:00 REGIONAL TOUR